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Gut-Brain Axis

Written by Dr. Brandon Rieders, Gastroenterologist

The connection between the gut and brain, known as the gut-brain axis, is a fascinating and growing area of research. The gut is often referred to as the “second brain” because it produces many of the same neurotransmitters as the brain, such as serotonin and dopamine, which play key roles in mood regulation. Stress can disrupt this delicate balance, leading to digestive issues such as bloating, cramping, and irregular bowel movements. Fortunately, natural ingredients like ashwagandha and L-theanine can help manage stress and its impact on the gut.

When you’re stressed, your body enters a fight-or-flight mode, which can negatively impact digestion. Stress can alter gut motility, increase gut permeability, and change the composition of the gut microbiome, all of which contribute to digestive discomfort. Chronic stress can exacerbate conditions such as irritable bowel syndrome (IBS), leading to persistent symptoms that are difficult to manage.

Studies have shown that ashwagandha, an adaptogenic herb, can help reduce cortisol levels, the primary hormone responsible for the stress response. Ashwagandha supplementation reduced cortisol levels by up to 30% in one clinical trial, leading to significant improvements in stress and anxiety levels . By lowering cortisol, ashwagandha can help reduce the impact of stress on the gut, allowing for better digestion and overall gut health.

L-theanine, an amino acid found in green tea, also plays a role in stress reduction. L-theanine supplementation could reduce stress and anxiety levels, according to studies, by promoting relaxation without causing drowsiness . This calming effect can help prevent stress-induced digestive issues, making it a valuable ingredient for maintaining gut health.

Happitum™ includes both ashwagandha and L-theanine to help manage stress and its effects on the gut. By addressing the gut-brain axis, Happitum™ not only helps improve digestion but also supports mental well-being. This holistic approach ensures that your gut and mind are in harmony, leading to better overall health.

Dr. Brandon Rieders is a board-certified Gastroenterologist, practicing in Long Island, NY. He specializes in treating conditions such as irritable bowel syndrome (IBS), GERD, and other gut-related disorders. Dr. Rieders is committed to utilizing both evidence-based medicine and natural remedies to help his patients achieve optimal gut health.

Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine, 34(3), 255–26 Kimura, K., Ozeki, M., Juneja, L. R., & Ohira, H. (2007). L-Theanine reduces psychological and physiological stress responses. Nutritional Neuroscience, 10(2), 53-60.