Probiotics vs. Prebiotics – How They Impact Gut Health

Written by Dr. Brandon Rieders, Gastroenterologist

Written by Dr. Brandon Rieders, Gastroenterologist

You’ve likely heard that a healthy gut is central to overall health—and you’ve probably seen terms like probiotic and prebiotic on everything from yogurt containers to supplement labels. But what do they really mean? And more importantly, what role do they play in supporting your digestion, immunity, and even your mental clarity?

The answer lies in your gut microbiome—a bustling ecosystem of trillions of bacteria that influence everything from how you digest food to how you feel each day. Keeping this microbiome balanced requires the right inputs—and that’s where probiotics and prebiotics come in.

Let’s explore what these terms really mean, how they work, and how to include them in your daily diet to support gut health naturally.

What Are Probiotics?

Probiotics are live beneficial bacteria that, when consumed in adequate amounts, support a healthy gut microbiome. Think of them as reinforcements—helpful microbes that crowd out harmful bacteria, support digestion, and regulate inflammation.

How Probiotics Help:

  • Improve digestion and bowel regularity
  • Support immune function (Hill et al., 2014)
  • Reduce bloating, gas, and symptoms of IBS (Didari et al., 2015)
  • Influence brain health via the gut-brain axis (Dinan & Cryan, 2017)

Common Food Sources of Probiotics:

  • Yogurt (with live active cultures)
  • Kefir (fermented milk or water-based)
  • Kimchi and sauerkraut (fermented vegetables)
  • Miso and tempeh (fermented soy products)
  • Probiotic supplements (in capsule, powder, or liquid form)

Not all fermented foods are probiotic—only those containing live, active cultures can be classified as such.

What Are Prebiotics?

Prebiotics are non-digestible fibers that feed the good bacteria already living in your gut. While probiotics are the bacteria themselves, prebiotics are the food those bacteria need to thrive.

They stimulate the growth and activity of beneficial microbes and play a key role in maintaining a healthy gut lining and balanced microbiota.

Benefits of Prebiotics:

  • Enhance gut microbial diversity
  • Improve bowel regularity and stool consistency
  • Support absorption of minerals like calcium and magnesium (Roberfroid et al., 2010)
  • Promote production of short-chain fatty acids (SCFAs) that reduce inflammation

Common Prebiotic-Rich Foods:

  • Garlic
  • Onions
  • Leeks
  • Asparagus
  • Bananas (especially underripe)
  • Whole oats
  • Chicory root
  • Jerusalem artichoke

Probiotics vs. Prebiotics: What’s the Difference?

FeatureProbioticsPrebiotics
What they areLive beneficial bacteriaNon-digestible plant fibers
FunctionAdd healthy microbesFeed existing healthy microbes
Food sourcesFermented foods (yogurt, kefir)Fiber-rich foods (onions, oats)
Primary roleRebalance gut floraFuel the growth of good bacteria

One isn’t better than the other—they’re complementary. You need both to maintain a thriving gut ecosystem.

How They Work Together for Gut Health

Prebiotics and probiotics act like partners: probiotics bring the good bacteria, and prebiotics make sure they have something to eat.

When both are present in the diet, they help:

  • Maintain a balanced microbiome
  • Strengthen the gut lining and reduce inflammation
  • Support digestion and nutrient absorption
  • Influence mood and mental well-being through the gut-brain axis

This synergy is often referred to as a synbiotic effect, which has been shown to be more effective than either one alone for improving GI function and immune modulation (Swanson et al., 2020).

Best Practices for Including Both in Your Diet

You don’t need expensive products to get what your gut needs. Start with real food:

Tips for Daily Gut Support:

  • Breakfast: Greek yogurt with sliced banana (probiotic + prebiotic)
  • Lunch: Quinoa bowl with garlic-roasted veggies and fermented pickles
  • Snack: Oats with kefir and berries
  • Dinner: Miso-glazed salmon with asparagus and sautéed leeks

Aim for variety, not perfection. Different probiotic strains and prebiotic fibers feed different types of bacteria—so mix it up!

Common Myths and Misconceptions

Let’s clear up a few popular myths:

Myth 1: “You only need probiotics.”

Truth: Probiotics alone can’t thrive without the right fuel. Prebiotics are essential to maintain their growth and survival.

Myth 2: “Supplements are better than food.”

Truth: Whole foods provide not only probiotics and prebiotics, but also fiber, polyphenols, and antioxidants that support the gut holistically.

Myth 3: “All fermented foods are probiotic.”

Truth: Not all fermentation processes preserve live bacteria. Shelf-stable sauerkraut or pasteurized kimchi may have little to no live cultures.

When to Consider Supplements

While food should be your foundation, supplements can help if:

  • You’ve taken antibiotics recently
  • You’re dealing with IBS, IBD, or SIBO
  • Your diet is restricted or lacks variety
  • You’re looking to target specific concerns like constipation or immunity

Choose supplements with:

  • Clinically studied strains (e.g., Lactobacillus rhamnosus GG, Bifidobacterium infantis)
  • Guaranteed CFUs (colony-forming units) through expiration
  • Transparent labeling and third-party testing

Always consult a healthcare professional for personalized advice.

Conclusion

Probiotics and prebiotics are two of the most powerful tools for nurturing a healthy gut. Together, they balance the microbiome, support immunity, and influence how you feel—both physically and emotionally.

Start with small, consistent changes: a bowl of yogurt, some sautéed garlic, or a spoonful of sauerkraut. Probiotics act as general support for your GI system, but for those times of need when your stomach acts up, support your gut with a supplement like Happitum™, which blends calming botanicals with digestive enzymes to help you feel your best from the inside out.

Because a healthy gut isn’t just about digestion—it’s the foundation for total-body wellness.

References

  • Hill, C., Guarner, F., Reid, G., Gibson, G. R., Merenstein, D. J., Pot, B., … & Sanders, M. E. (2014). The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature Reviews Gastroenterology & Hepatology, 11(8), 506–514.
  • Didari, T., Mozaffari, S., Nikfar, S., & Abdollahi, M. (2015). Effectiveness of probiotics in irritable bowel syndrome: updated systematic review with meta-analysis. World Journal of Gastroenterology, 21(10), 3072–3084.
  • Roberfroid, M., Gibson, G. R., Hoyles, L., McCartney, A. L., Rastall, R., Rowland, I., … & Cummings, J. H. (2010). Prebiotic effects: metabolic and health benefits. British Journal of Nutrition, 104(S2), S1–S63.
  • Dinan, T. G., & Cryan, J. F. (2017). Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration. The Journal of Physiology, 595(2), 489–503.
  • Swanson, K. S., Gibson, G. R., Hutkins, R., Reimer, R. A., Reid, G., Verbeke, K., & Scott, K. P. (2020). The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics. Nature Reviews Gastroenterology & Hepatology, 17(11), 687–701.